Ticlopidine hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

噻氯匹定是一种有效的血小板聚集抑制剂。

Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke. The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients’ WBC and platelets when they are taking ticlopidine.

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Neuroscience

P2 Receptor

P2 receptor

Cardiovascular Disease

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53885-35-1

300.25

C14H15Cl2NS

>98% (HPLC)

Ethanol: 1 mg/mL (3.33 mM); Water: 4 mg/mL (13.32 mM); DMSO: 1 mg/mL (3.33 mM)

Cl.ClC1=CC=CC=C1CN1CCC2=C(C1)C=CS2

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(-20℃)

With Ice Pack

≥ 2 years